More than 35 years of clinical experience have made Canesten® what it is today: an effective, well tolerated and safe drug product for fungal infections.
Modern antifungal research got underway after World War II and then intensified in the 1950s and 1960s as a result of the massive increase in fungal infections. Bayer was amongst those who responded to this challenge and established a research laboratory for medicinal mycology in 1963. The breakthrough to active substances with a broad spectrum of antifungal action was achieved with the discovery of the azole derivatives by the Bayer researcher Prof. Karl Heinz Büchel who succeeded in synthesising the first azole derivative, clotrimazole, in the late 1960s.
Clotrimazole was registered in Germany for the first time in 1973 and launched on the market under the brand name Canesten®. The first presentations for treatment of fungal skin infections were the Cream and Solution (Pumpspray), while Canesten® Vaginal Tablets were developed for treatment of gynaecological fungal vaginal infections. In the late 1970s, the range was extended by the addition of the Canesten® Solution with Atomiser and Canesten® Vaginal Cream.
Thanks to their excellent efficacy and tolerability, the dermatological Canesten® products were registered for self-medication in 1977. The gynaecological presentations for 1-day and 3-day therapy were initially granted Over-the-Counter status (available without description) in Great Britain in 1992, followed two years later by similar approval in Germany. Canesten® is now available without prescription in most countries.
Canesten® is the market leader for treatment of dermatological and gynaecological fungal infections. Canesten® contains the original active ingredient clotrimazole developed by Bayer. Clotrimazole was introduced into the market in 1973 world-wide. Today, clotrimazole is the reference active ingredient in topical antifungal therapy.
The variety of the product range allows fast, reliable and convenient use against fungal diseases. Today, Canesten® is available in more than 80 countries. Bayer researchers continuously develop innovative and effective remedies for new areas of application for all types of fungal diseases.
In the area of fungal infections Canesten offers a complete range of solutions. Here, we have compiled interesting facts and comprehensive background information.
What is Sweat Rash?
Sweat rash is extremely common. Unfortunately it can affect anyone at any time but there is no reason why it should cause long-lasting discomfort. This irritating condition is caused by candida, a yeast that occurs naturally on your skin. Trapped perspiration can sometimes upset the natural balance of the skin allowing candida to cause an irritating, itchy and often unsightly red rash. It's difficult to know when it might strike as everyday things such as sweating it out at the gym could potentially lead to this common fungal skin infection. Common areas where this tends to appear are where the skin rubs together: under the arms, backs of the knees, groin and under the breasts.
Who gets sweat rash?
Anyone could get sweat rash at anytime. It is often caused by candida (a yeast that lives naturally on your skin). Things such as rushing for the bus, working out at the gym and even wearing tight fitting clothing can all upset the natural balance of candida on the skin. This can result in a red, sore, itchy rash that can drive you to distraction. People who sweat more are more likely to suffer - candidal sweat rash is therefore more common in sporty people, the overweight or the immobile but as candida lives naturally on the skin it could be experienced by anyone especially during the summer time.
SYMPTONS OF SWEAT RASH
- Candidal sweat rash is caused by an overgrowth of candida. Candida may overgrow and cause a problem when the condition of the skin changes i.e. the area becomes warmer or more moist than normal.
- A key cause of a candidal overgrowth is sweating which is why it is more common in the summer months or amongst sporty people.
The common signs and symptoms of sweat rash are:
- A sore red rash
- Inflamed skin
- Burning discomfort
- The skin could also be broken and may be moist
Sweat rash is usually found in skin folds or in areas where skin rubs together, therefore you are more likely to experience this condition in areas such as:
- Under arms, between and under breasts
- Back of knees
What is Athlete's foot?
- Athlete's foot is one of those irritating skin problems that just seem to appear and then stubbornly refuse to go away.
- Athlete's foot is a common fungal infection of the skin, typically appearing between the toes but also on the soles and sides of the feet.
Who gets athlete's foot?
Anyone can get it however, active people, for instance, who take part in sports can be more susceptible, as well as those who work in warm, damp environments.
How does the infection occur?
The infection and its symptoms are caused by a contagious fungus that thrives in warm, moist environments. In fact, any place where people walk barefoot can be a source of infection.
What are the symptoms of athlete's foot?
The most irritating symptom of athlete's foot is itchy feet, but if left untreated the skin may start to flake or become cracked and painful. Occasionally it may become infected with bacteria, which you notice by an unpleasant odour.
The people disease that anyone can get
Fungal infections of the skin are simply among the most common ailments. Surprisingly, studies show that as much as 25 % of the population has athlete's foot. Among swimmers and miners, the frequency is even higher.
The good news is that you don't have to be embarrassed. Nevertheless, you should still do something about it!
Some facts about athlete`s foot
- Athlete`s foot is one of the most common ailments of all.
- Every fourth person suffers from athlete`s foot.
- The fungi are transmitted by way of infected flakes of skin.
- The most typical places for athlete`s foot to be spread are swimming pools, public sports facilities, hotel rooms, saunas, and locker rooms, or even in the home, where it can be spread from one family member to another.
- Athlete`s foot is easy to treat with modern anti-fungal products.
How to recognize athlete’s foot?
Typical signs of athlete`s foot are the redness on the skin and grayish white flakes, as well as the itchiness and burning sensation especially between the toes. Athlete`s foot usually appears in between the fourth and fifth toes, but other parts of the foot can be affected as well. If the infection goes untreated, the fungus may eventually spread to the nail.
The four most important athlete`s foot symptoms
- Greyish white flakes
- Burning Most often between the fourth and fifth toes
The treatment is really simple
At the first sign of athlete`s foot, you should begin a targeted and consistent treatment so that the infection does not spread any further. In order to do this, an anti-fungal medication is necessary. This kind of a product, such as Canesten®, can be obtained at your pharmacy without a prescription.
Canesten®, a state of the art anti-fungal product, contains an active ingredient that is particularly effective against dermatophytes, which are the most common pathogens in athlete`s foot infections, and also against yeasts, moulds, and some bacteria.
The newest product in the Canesten® line, Canesten® Extra, needs to be applied just once a day, since the active ingredient persists in the skin for a particularly long time. Aside from that, Canesten® Extra works simultaneously against the inflammation associated with athlete`s foot and the unpleasant itchiness and burning symptoms.
So that athlete`s foot completely disappears, the therapy must be carried out regularly and for long enough. Therefore, it is advisable to wait for two weeks after the disappearance of visible symptoms on the skin until you stop treatment. The athlete`s foot should be healed after a total of between 3 and 4 weeks.