Spedra 100mg Tablets

SKU : PGD-SPED100MG

Spedra is a treatment for adult men suffering from erectile dysfunction (also known as impotence). This is when you cannot get, or keep a hard, erect penis suitable for sexual activity.

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PGD-SPED100MG
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Description

Spedra 100mg Tablets

Spedra is a treatment for adult men suffering from erectile dysfunction (also known as impotence). This is when you cannot get, or keep a hard, erect penis suitable for sexual activity. Spedra contains the active substance avanafil. It belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors and works by helping the blood vessels in your penis to relax. This increases the blood flow into your penis, helping it stay hard and erect when you get sexually excited.

Spedra only works if you are sexually stimulated, so you and your partner will still need to use foreplay to get ready for sex, just as you would if you were not taking a medicine to help you.

Directions

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

  • You should take Spedra approximately 15 to 30 minutes before you have sexual intercourse. 
  • Spedra can be taken with or without food. If taken with food, it may take longer to work.
  • You should not take Spedra more than once a day.

Tell your doctor if you think Spedra is too strong or too weak. He/she may suggest you switch to a different dose of this medicine.

Ingredients

  • Active Ingredient: Avanafil 100mg
  • Other Ingredients: Mannitol, fumaric acid, hydroxypropylcellulose, low substituted hydroxypropylcellulose, calcium carbonate, magnesium stearate and ferric oxide yellow (E172).

Cautions

  • Some men taking medicines like Spedra have had problems with their sight and hearing. It is not known if these problems are related directly to Spedra, other diseases that you may have or a combination of factors.
  • Spedra should not be taken by children and adolescents under 18 years of age.
  • Do not use Spedra together with other treatments for erectile dysfunction such as sildenafil, tadalafil or vardenafil.
  • Grapefruit juice can increase exposure to the medicine and should be avoided within 24 hours prior to taking Spedra.
  • Drinking alcohol at the same time as taking Spedra may increase your heart rate and lower your blood pressure. You may feel dizzy (especially when standing), have a headache or feel your heart beating in your chest (palpitations). Drinking alcohol may also decrease your ability to get an erection.
  • Spedra can make you feel dizzy or affect your vision. If this happens, do not drive, cycle, use tools or machines.

Do not take Spedra:

  • If you are allergic to avanafil or any of the other ingredients of this medicine.
  • If you are taking “nitrate” medicines for chest pain (angina), such as amyl nitrite or glyceryl trinitrate. Spedra can increase the effects of these medicines and severely lower your blood pressure.
  • If you are taking medicines for HIV or AIDS such as ritonavir, indinavir, saquinavir, nelfinavir or atazanavir.
  • If you are taking medicines for fungal infections such as ketoconazole, itraconazole or voriconazole or certain antibiotics for bacterial infections, such as clarithromycin or telithromycin.
  • If you have a serious cardiac problem.
  • If you have had a stroke or heart attack in the last 6 months.
  • If you have low blood pressure or high blood pressure not controlled by medicines.
  • If you have chest pain (angina) or you get chest pain during sexual intercourse.
  • If you have a serious liver or kidney problem.
  • If you have loss of vision in one eye due to not enough blood getting to your eye (non-arteritic ischemic optic neuropathy [NAION]).
  • If certain serious eye problems run in your family (such as retinitis pigmentosa).
  • If you are taking riociguat. This drug is used to treat pulmonary arterial hypertension (i.e. high blood pressure in the lungs) and chronic thromboembolic pulmonary hypertension (i.e. high blood pressure in the lungs secondary to blood clots). PDE5 inhibitors have been shown to increase the hypotensive effects of this medicine. If you are taking riociguat or are unsure tell your doctor.

Talk to your doctor or pharmacist before taking Spedra:

  • If you have heart trouble. It may be risky for you to have sexual intercourse.
  • If you suffer from priapism, that is a persistent erection lasting 4 hours or more. This can happen in men with conditions like sickle cell disease, multiple myeloma or leukaemia.
  • If you have a physical condition that affects the shape of your penis (such as angulation, Peyronie's disease or cavernosal fibrosis).
  • If you have any bleeding disorder or active peptic ulceration.

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This is because Spedra can affect the way some other medicines work. Also some other medicines can affect the way Spedra works. In particular, tell your doctor or pharmacist if you are taking any of the following medicines:

  • So called "alpha-blockers" – for prostate problems or for lowering your high blood pressure.
  • Medicines for an irregular heartbeat (“arrhythmia”) such as quinidine, procainamide, amiodarone or sotalol.
  • Antibiotics for infections such as erythromycin.
  • Phenobarbital or primidone – for epilepsy.
  • Xarbamazepine – for epilepsy, to stabilise your mood or for certain types of pain.
  • Other medicines that may reduce the breakdown of Spedra in the body ('moderate CYP3A4 inhibitors') including amprenavir, aprepitant, diltiazem, fluconazole, fosamprenavir, and verapamil.
  • Riociguat.

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